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Related Concept Videos

Spinal Cord Injury ll: Pathophysiology01:14

Spinal Cord Injury ll: Pathophysiology

Spinal cord injury progresses through two interconnected phases: primary injury and secondary injury.Primary InjuryPrimary injury happens at the moment of trauma and involves immediate mechanical damage to the spinal cord.Compression happens when broken vertebrae, herniated discs, or accumulating blood (such as a hematoma) press directly against the spinal cord, distorting its normal shape and function. In cases of contusion, the cord is bruised by a blunt force (like penetrating injuries or...
Secondary Spinal Cord Injury llI: Pathophysiology01:25

Secondary Spinal Cord Injury llI: Pathophysiology

Early Ischemia and Ionic ImbalanceWithin minutes of spinal cord injury, a secondary cascade begins, progressing over hours to weeks. Vascular damage reduces blood flow, causing ischemia and mitochondrial dysfunction. ATP depletion leads to ion pump failure, membrane depolarization, sodium influx, potassium efflux, and water accumulation, resulting in cellular swelling. Increased intracellular calcium further disrupts mitochondria and accelerates cellular injury.Excitotoxicity and Neuronal...

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Updated: May 12, 2026

A Novel Vertebral Stabilization Method for Producing Contusive Spinal Cord Injury
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Spinal Cord Injury Following Minimally Invasive Spinal Decompression.

Roger Liu1, Marya Ghazzi2, Tomasz Chec3

  • 1Department of Rehabilitation Medicine, Thomas Jefferson University Hospital, Philadelphia, PA.

Pain Medicine Case Reports
|November 27, 2025
PubMed
Summary
This summary is machine-generated.

Spinal cord injury is a rare complication following minimally invasive lumbar decompression (MILD). This case highlights potential risks in patients with severe lumbar spinal stenosis, necessitating careful consideration of patient factors.

Area of Science:

  • Neurosurgery
  • Interventional Radiology
  • Spinal Surgery

Background:

  • Minimally invasive lumbar decompression (MILD) is an established treatment for symptomatic lumbar spinal stenosis.
Keywords:
MILDinterventional procedurespinal cord injuryspinal stenosis

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  • Spinal cord injury is an undocumented complication of the MILD procedure in existing literature.