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Routine Hair Testing Unmasks Hidden Synthetic Cannabinoid Use in Forensic Psychiatric Patients: A 10-Year Comparative
Michael Fritz1, Hannah Funk1, Felipe Montiel2
1Department of Forensic Psychiatry and Psychotherapy, Ulm University, 89312 Guenzburg, Germany.
Brain Sciences
|November 27, 2025
Summary
Standardized hair analysis and broad-spectrum screenings significantly improve synthetic cannabinoid (SC) detection rates in forensic psychiatric patients undergoing therapy. A history of violence is a key predictor for SC relapse during reintegration.
Area of Science:
- Forensic Psychiatry
- Addiction Medicine
- Criminal Justice
Background:
- Germany's § 64 Criminal Code mandates two-year multimodal therapy for offenders with substance use disorders.
- The reintegration phase involves reduced supervision, where lapses, particularly synthetic cannabinoid (SC) use, are often concealed due to detection challenges.
Purpose of the Study:
- To compare the effectiveness of different monitoring strategies for synthetic cannabinoid (SC) use in forensic psychiatric patients.
- To evaluate the impact of standardized hair analysis versus case-dependent urine testing on SC detection rates.
Main Methods:
- A ten-year comparative study (2014-2024) of two forensic hospitals (Guenzburg and Kaufbeuren).
- Guenzburg implemented mandatory hair analysis and broad-spectrum SC screenings from 2019, while Kaufbeuren used case-dependent urine testing.
- 527 patients were included in the analysis.
Main Results:
- Guenzburg conducted significantly more tests and achieved a seven-fold higher SC detection rate using hair analysis compared to Kaufbeuren's urine testing.
- SC-positive patients were younger at first conviction, more often under substitution treatment, and had a higher likelihood of violent offenses.
- A history of violence quadrupled the odds of SC positivity.
Conclusions:
- Standardized long-term SC monitoring, particularly using hair analysis, is effective in forensic psychiatric settings.
- A history of violence is a significant predictor of SC relapse during the reintegration phase.
- Targeted monitoring strategies can improve detection and management of SC use in this population.

