Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

X-Inactivation01:58

X-Inactivation

The human X chromosome contains over ten times the number of genes as in the Y chromosome. Since males have only one X chromosome, and females have two, one might expect females to produce twice as many of the proteins, with undesirable results.
Inheritance of Chromatin Structures03:17

Inheritance of Chromatin Structures

Epigenetics is the study of inherited changes in a cell's phenotype without changing the DNA sequences. It provides a form of memory for the differential gene expression pattern to maintain cell lineage, position-effect variegation, dosage compensation, and maintenance of chromatin structures such as telomeres and centromeres. For example, the structure and location of the centromere on chromosomes are epigenetically inherited. Its functionality is not dictated or ensured by the underlying DNA...
X and Y Chromosomes02:32

X and Y Chromosomes

Among mammals, the gender of an organism is determined by the sex chromosomes. Humans have two sex chromosomes, X and Y. Every human diploid cell has 22 pairs of autosomes and one pair of sex chromosomes. A human female has two X chromosomes, while a male has one X chromosome and one Y chromosome.
The germline cells such as egg and sperm cells carry only half the number of chromosomes, i.e., 22 autosomes and one sex chromosome. All eggs have an X chromosome, while sperm cells can carry an X or...
The Y Chromosome Determines Maleness02:19

The Y Chromosome Determines Maleness

The Y chromosome is a sex chromosome found in several vertebrates and mammals, including humans. In addition to 22 pairs of autosomes, the human males have one X chromosome and one Y chromosome. In these organisms, the presence or absence of the Y chromosome determines the development of male traits.
Evolution
Around 300 million years ago, the two sex chromosomes diverged from two identical autosomal chromosomes. Over time, the Y chromosome has lost most of its genes, shrinking in size. Today,...
X-inactivation01:58

X-inactivation

The human X chromosome contains over ten times the number of genes as in the Y chromosome. Since males have only one X chromosome, and females have two, one might expect females to produce twice as many of the proteins, with undesirable results.
Heterochromatin02:38

Heterochromatin

The extent of chromatin compaction can be studied by staining chromatin using specific DNA binding dyes. Under the microscope, the dense-compacted regions that take up more dye are called heterochromatin. Heterochromatin is further classified into two forms – constitutive heterochromatin and facultative heterochromatin.
Constitutive heterochromatin: It is a highly compact region of chromatin that is mostly concentrated in the centromere and telomere. Unlike euchromatin, the amino acid at 9th...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Oral bisphosphonate use and lung cancer incidence among postmenopausal women.

Annals of oncology : official journal of the European Society for Medical Oncology·2018
Same author

The impact of birth weight on cardiovascular disease risk in the Women's Health Initiative.

Nutrition, metabolism, and cardiovascular diseases : NMCD·2015
Same author

Continuous Combined Estrogen Plus Progestin and Endometrial Cancer: The Women's Health Initiative Randomized Trial.

Journal of the National Cancer Institute·2015
Same author

Repeated measurements of serum carotenoid, retinol and tocopherol levels in relation to colorectal cancer risk in the Women's Health Initiative.

European journal of clinical nutrition·2011
Same author

Academic models of clinical care for women: the National Centers of Excellence in Women's Health.

Journal of women's health & gender-based medicine·2001
Same author

Managing depression in outpatients.

The New England journal of medicine·2001

Related Experiment Video

Updated: Jul 25, 2026

Slide Preparation Method to Preserve Three-dimensional Chromatin Architecture of Testicular Germ Cells
07:34

Slide Preparation Method to Preserve Three-dimensional Chromatin Architecture of Testicular Germ Cells

Published on: January 10, 2014

Apparently isodicentric but functionally monocentric X chromosome in man

E Therman, G E Sarto, K Patau

    American Journal of Human Genetics
    |January 1, 1974
    PubMed
    Summary

    No abstract available in PubMed .

    More Related Videos

    Combined DNA-RNA Fluorescent In situ Hybridization (FISH) to Study X Chromosome Inactivation in Differentiated Female Mouse Embryonic Stem Cells
    15:54

    Combined DNA-RNA Fluorescent In situ Hybridization (FISH) to Study X Chromosome Inactivation in Differentiated Female Mouse Embryonic Stem Cells

    Published on: June 14, 2014

    A Non-random Mouse Model for Pharmacological Reactivation of Mecp2 on the Inactive X Chromosome
    08:27

    A Non-random Mouse Model for Pharmacological Reactivation of Mecp2 on the Inactive X Chromosome

    Published on: May 22, 2019

    Related Experiment Videos

    Last Updated: Jul 25, 2026

    Slide Preparation Method to Preserve Three-dimensional Chromatin Architecture of Testicular Germ Cells
    07:34

    Slide Preparation Method to Preserve Three-dimensional Chromatin Architecture of Testicular Germ Cells

    Published on: January 10, 2014

    Combined DNA-RNA Fluorescent In situ Hybridization (FISH) to Study X Chromosome Inactivation in Differentiated Female Mouse Embryonic Stem Cells
    15:54

    Combined DNA-RNA Fluorescent In situ Hybridization (FISH) to Study X Chromosome Inactivation in Differentiated Female Mouse Embryonic Stem Cells

    Published on: June 14, 2014

    A Non-random Mouse Model for Pharmacological Reactivation of Mecp2 on the Inactive X Chromosome
    08:27

    A Non-random Mouse Model for Pharmacological Reactivation of Mecp2 on the Inactive X Chromosome

    Published on: May 22, 2019