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Published on: August 8, 2025
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Microvascular Imaging of Hepatic Hemangiomas
Hakan Baş1,2, Süleyman Filiz1
1Department of Radiology, Gazi Mustafa Kemal Occupational and Environmental Diseases Hospital, Silahtar Street No:6, Emniyet, Yenimahalle, 06560 Ankara, Türkiye.
Diagnostics (Basel, Switzerland)
|November 27, 2025
Summary
Microvascular imaging (MI) effectively detects hemangioma vascularity, with detection rates decreasing for deeper lesions. This contrast-free technique is reproducible and valuable when contrast agents are unavailable or contraindicated.
Area of Science:
- Radiology
- Medical Imaging
- Hepatology
Background:
- Hepatic hemangiomas are common benign liver tumors.
- Assessing their vascularity is crucial for diagnosis.
- Microvascular imaging (MI) offers a contrast-free approach.
Purpose of the Study:
- To characterize microvascular imaging (MI) findings in hepatic hemangiomas.
- To quantify the impact of lesion depth on MI signal detectability.
- To describe the distribution of MI appearances in hepatic hemangiomas.
Main Methods:
- Retrospective analysis of 72 hepatic hemangiomas from 61 patients.
- Independent assessment of MI signals and patterns by two radiologists using Jeon classification.
- Inter-observer agreement quantified using Cohen's kappa.
Main Results:
- Microvascular imaging (MI) detected signals in 94.4% of hemangiomas.
- Common MI patterns included non-specific, nodular rim, and strip rim.
- Signal-negative lesions were significantly deeper than signal-positive lesions (median 85 mm vs. 41.5 mm).
- Very good inter-observer agreement (κ = 0.821) was achieved.
Conclusions:
- Microvascular imaging (MI) is a reproducible, contrast-free technique for demonstrating hemangioma vascularity.
- Lesion depth, not size, was the primary determinant of MI signal detectability.
- MI is a valuable complementary tool to CT/MRI, especially when contrast is contraindicated.

