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Characterization of Peripheral Retinal Degenerations and Rhegmatogenous Lesions Using Ultra-Widefield Swept Source
Daniela Bacherini1,2, Clara Rizzo1,2, Giulio Vicini1,2
1Eye Clinic, Neuromuscular and Sense Organs Department, Careggi University Hospital, Largo Brambilla 3, 50134 Florence, Italy.
Diagnostics (Basel, Switzerland)
|November 27, 2025
Summary
Ultra-widefield swept-source optical coherence tomography (SS-OCT) effectively characterizes peripheral retinal degenerations and rhegmatogenous lesions. This advanced imaging modality improves detection and provides crucial details influencing clinical management decisions.
Area of Science:
- Ophthalmology
- Medical Imaging
- Retinal Diseases
Background:
- Peripheral retinal degenerations and rhegmatogenous lesions are difficult to visualize with conventional methods.
- Advanced imaging is needed for improved detection and characterization of these lesions.
Purpose of the Study:
- To evaluate ultra-widefield swept-source optical coherence tomography (SS-OCT) for characterizing peripheral retinal degenerations and rhegmatogenous lesions.
- To assess the implications of SS-OCT findings for clinical management.
Main Methods:
- Retrospective observational study of 107 eyes from 95 patients with peripheral retinal degenerations and/or rhegmatogenous lesions.
- Comprehensive ophthalmological evaluation including peripheral SS-OCT imaging.
- Assessment of vitreoretinal attachment, vitreous traction, retinal defects, and subretinal fluid.
Main Results:
- SS-OCT successfully characterized 130 retinal lesions, including retinal tears, lattice degeneration, and retinal holes.
- High-resolution visualization revealed vitreous traction and subretinal fluid not always clinically detectable.
- SS-OCT findings influenced management decisions in several cases.
Conclusions:
- Ultra-widefield SS-OCT significantly enhances visualization of peripheral retinal lesions.
- Provides clinically meaningful details that can impact diagnosis and decision-making.
- Demonstrates the potential of SS-OCT as a valuable tool in managing peripheral retinal pathologies.
