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Updated: Jan 10, 2026

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
Ethical AI in Healthcare: Integrating Zero-Knowledge Proofs and Smart Contracts for Transparent Data Governance
Mohamed Ezz1, Alaa S Alaerjan1, Ayman Mohamed Mostafa2
1Department of Computer Science, College of Computer and Information Sciences, Jouf University, Sakaka 72388, Saudi Arabia.
Abstract:
In today's rapidly advancing healthcare landscape, integrating Artificial Intelligence (AI) and Machine Learning (ML) has the potential to significantly improve patient care and streamline medical processes. The utilization of confidential patient data to train and develop these technologies, however, raises significant concerns regarding authenticity, security, and privacy. In this study, we introduce MediChainAI, a safe and practical framework that allows patients full ownership over their own health data by integrating Self-Sovereign Identity (SSI), Blockchain, and sophisticated cryptography techniques. By clearly outlining the goals and parameters of this access, MediChainAI allows patients to safely and selectively share data with healthcare providers and researchers. While SSI guarantees that patients have ownership of their data, the framework uses Blockchain technology to keep things transparent and secure. Further, MediChainAI makes use of Merkle trees, which provide verified access to subsets of data without jeopardizing the privacy of the whole dataset. The encryption mechanism, which is based on smart contracts, is a distinctive feature of the framework that allows researchers and medical practitioners controlled and secure access to patient data. In order to improve the accuracy and reliability of medical diagnoses and treatment, this strategy makes sure that only confirmed, legitimate data is utilized to train medical models. A significant step toward safer and more personalized healthcare, MediChainAI encourages ethical and patient-focused innovation by effectively resolving essential issues regarding data security and patient privacy.
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