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Updated: Jan 10, 2026

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
Published on: March 15, 2022
Intravascular Imaging Guidance for Percutaneous Coronary Interventions
Marco Spagnolo1, Daniele Giacoppo1, Antonio Greco1
1Division of Cardiology, Azienda Ospedaliero-Universitaria Policlinico "G. Rodolico-San Marco", University of Catania, 95123 Catania, Italy.
Intravascular imaging (IVI), including intravascular ultrasound (IVUS) and optical coherence tomography (OCT), provides detailed vessel and plaque information for percutaneous coronary intervention (PCI). IVI use is recommended for complex cases, but adoption is limited, necessitating further research on cost-effectiveness.
Area of Science:
- Cardiovascular Imaging
- Interventional Cardiology
- Medical Device Technology
Background:
- Two-dimensional coronary angiography has limitations in assessing coronary anatomy and stent placement.
- Intravascular imaging (IVI) modalities like intravascular ultrasound (IVUS) and optical coherence tomography (OCT) offer high-resolution insights.
- These insights can improve procedural success and long-term outcomes in percutaneous coronary intervention (PCI).
Purpose of the Study:
- To review the capabilities and clinical applications of IVI in coronary interventions.
- To compare the strengths and weaknesses of IVUS and OCT.
- To discuss the factors influencing IVI adoption and future research directions.
Main Methods:
- Review of current literature on IVI techniques (IVUS and OCT).
- Comparison of imaging characteristics and clinical utility.
- Discussion of guideline recommendations and real-world implementation challenges.
Main Results:
- IVI provides superior anatomical and morphological information compared to angiography, especially in complex lesions.
- IVUS excels in deep penetration and real-time imaging for large vessels and chronic total occlusions.
- OCT offers high resolution for plaque characterization and stent complication detection.
Conclusions:
- IVI plays a crucial role in complex coronary interventions, guiding PCI and assessing stent outcomes.
- Hybrid IVUS-OCT systems may combine complementary strengths.
- Low adoption rates highlight the need for further research into optimal use, cost-effectiveness, and training.
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