The Concept of a 3D-Printed Microfluidic Device on Oxyfluorinated PDMS Substrates

We present the concept of a microfluidic device manufactured using 3D printing and oxyfluorination techniques. During prototype testing, it was found that a larger number of cells adhered to the oxyfluorinated surface compared to the original one. It has also been shown that longer gas-phase treatments correspond to a higher level of cell growth. These items can be used in experiments with reagents and/or microorganisms that cause glass surface corrosion. This increases the number of production techniques for microfluidics devices, expands the possibilities for their use in biotechnology, and solves the main problem of low interlayer adhesion between components of polymer-made microfluidic devices.