Related Experiment Video
Updated: Jan 10, 2026

Generating Transposon Insertion Libraries in Gram-Negative Bacteria for High-Throughput Sequencing
Published on: July 7, 2020
Unveiling the Mechanisms of Bacterial Resistance and Countermeasures
Yuqing Xie1, Hao Lu2, Yichen Liu1
1College of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China.
None:
The discovery and clinical deployment of antibiotics marked a paradigm shift in combating bacterial infections, profoundly benefiting human medicine, veterinary health, and agricultural productivity. However, pervasive overuse in both the clinical and livestock sectors has precipitated an alarming acceleration of antimicrobial resistance, now recognized as a critical global health threat. Compounding this crisis, livestock-associated resistant pathogens persistently colonize the food production continuum, enabling zoonotic transmission through animal-derived products and endangering public health, food safety, and human survival. This review delineates current insights into bacterial resistance mechanisms and evaluates innovative countermeasures, aiming to inform future antimicrobial development and resistance containment strategies.
Related Concept Videos
Development of Antibiotic Resistance
Defense Against Bacterial Pathogens
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
Antibiotic Selection
Biological Methods for Microbial Control
Gene Regulation in Microbial Communities: Quorum Sensing
Coordination of Gene Expression Processes in Bacteria

