Clinical Characteristics of Paediatric RSV, Influenza, and SARS-CoV-2 Infections: Insights from Three Consecutive Seasons
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View abstract on PubMed
Summary
This summary is machine-generated.Respiratory Syncytial Virus (RSV) infections in children often present with severe respiratory symptoms and delayed hospital admission. Influenza and SARS-CoV-2 typically show milder upper respiratory symptoms, with distinct age-related patterns observed for each virus.
Area Of Science
- Pediatrics
- Infectious Diseases
- Respiratory Medicine
Background
- Retrospective analysis of clinical presentations of three major respiratory viruses in children.
- Covers three consecutive winter seasons (2022-2025).
Purpose Of The Study
- To compare the clinical manifestations of RSV, Influenza, and SARS-CoV-2 in hospitalized children.
- To identify age-specific patterns in disease presentation for each virus.
Main Methods
- Analysis of 321 hospitalized children (≤17 years).
- Statistical methods included Chi-squared test and multivariable logistic regression.
- Odds ratios (OR) and 95% confidence intervals (CI) were calculated.
Main Results
- RSV was linked to abnormal lung sounds and delayed admission (≥4 days).
- RSV in infants (<6 months) showed higher CRP, reduced appetite, and prolonged fever compared to older children.
- Influenza and COVID-19 (SARS-CoV-2) showed milder symptoms, with specific age-related findings like higher CRP in COVID-19 patients.
Conclusions
- RSV presents with more severe respiratory illness and later hospitalizations.
- Influenza and SARS-CoV-2 generally have milder courses with upper respiratory symptoms.
- Virus-specific and age-specific patterns underscore the need for ongoing surveillance and comparative research.
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