Temporal, Spatial and Seasonal Patterns of Parvovirus B19 Seroepidemiology in Childbearing-Aged Women in Croatia, 2015-2024
These videos have been matched automatically. Contact us if they are not relevant.
These videos have been matched automatically. Contact us if they are not relevant.
View abstract on PubMed
Summary
This summary is machine-generated.Parvovirus B19 (B19V) infection is a concern in pregnancy. This study found high IgG seroprevalence in Croatian women, increasing with age, and identified seasonal patterns for acute infections, supporting targeted testing.
Area Of Science
- Infectious Diseases
- Epidemiology
- Public Health
Background
- Parvovirus B19 (B19V) infection during pregnancy poses risks to fetal development and pregnancy outcomes.
- Understanding the seroepidemiology of B19V is crucial for managing risks in pregnant populations.
Purpose Of The Study
- To analyze the temporal, spatial, and seasonal seroepidemiology of Parvovirus B19 in childbearing-aged and pregnant women in Croatia.
- To identify risk factors and trends associated with B19V infection in this demographic.
Main Methods
- A 10-year study (2015-2024) analyzed 976 women undergoing TORCH screening.
- Seroprevalence of B19V IgG and IgM antibodies was determined.
- Statistical analysis, including logistic regression, was used to assess temporal, spatial, and demographic factors.
Main Results
- Overall B19V IgG and IgM seroprevalence was 63.7% and 8.7%, respectively.
- IgG seropositivity increased significantly with age (42.3% in 16-20 years to 72.7% in 36-40 years).
- Acute infections peaked from March to July, with regional seasonal variations; no significant spatial differences were found.
Conclusions
- Age is a significant predictor of B19V IgG seroprevalence.
- Targeted serologic testing for B19V is recommended for pregnant women with symptoms, known exposure, or occupational risk due to high susceptibility.
These videos have been matched automatically. Contact us if they are not relevant.
These videos have been matched automatically. Contact us if they are not relevant.
Related Concept Videos
Retroviruses have a single-stranded RNA genome that undergoes a special form of replication. Once the retrovirus has entered the host cell, an enzyme called reverse transcriptase synthesizes double-stranded DNA from the retroviral RNA genome. This DNA copy of the genome is then integrated into the host’s genome inside the nucleus via an enzyme called integrase. Consequently, the retroviral genome is transcribed into RNA whenever the host’s genome is transcribed, allowing the...
In statistical epidemiology and health sciences, two essential metrics—prevalence and incidence—are fundamental for understanding disease dynamics within a population. These measures enable public health officials, epidemiologists, and researchers to assess the burden of diseases, allocate resources effectively, and design impactful public health policies and interventions.
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
Epidemiological data primarily involves information on specific populations' occurrence, distribution, and determinants of health and diseases. This data is crucial for understanding disease patterns and impacts, aiding public health decision-making and disease prevention strategies. The analysis of epidemiological data employs various statistical methods to interpret health-related data effectively. Here are some commonly used methods:
Descriptive Statistics: These provide basic...
Real-time reverse transcription-polymerase chain reaction, or Real-time RT-PCR, is an analytical tool used to determine the expression level of target genes. The method involves converting mRNA to complementary DNA with the help of an enzyme known as reverse transcriptase, followed by the PCR amplification of the cDNA. These two processes can be performed simultaneously in a single tube or separately as a two-step reaction.
The real-time quantification of the number of amplified products is...
Before understanding the types and patterns of fever, it is essential to know its phases.
• The first stage is the onset/invasion phase, during which the body temperature rises. It might be a sudden or gradual process.
• The second stage is the steady phase, during which the body temperature has reached its maximum and remains constant at a high level.
• The third stage is the defervescence or decline phase, during which the elevated temperature returns to...
Disease surveillance is the systematic collection, analysis, and interpretation of health data essential to the planning, implementation, and evaluation of public health practice. This process integrates data dissemination to entities responsible for preventing and controlling disease, injury, and disability. Surveillance systems provide crucial information for action, helping public health authorities make informed decisions to manage and prevent outbreaks, ensure public safety, optimize...