Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Exploring the Potential of Cerium-Zinc Co-Incorporated Titanium Implants for Enhanced Antibacterial Activity, Cytocompatibility, and Bone Regeneration.

Journal of biomedical materials research. Part B, Applied biomaterials·2026
Same author

Multifunctional Ti metal with magnesium and cerium co-incorporation: a bioactive surface modification approach for improved <i>in vitro</i> and <i>in vivo</i> performances.

Biomaterials science·2026
Same author

Strontium-cerium surface functionalization of titanium scaffold: unlocking the potential of element incorporation for bone implant application.

Biomaterials advances·2025
Same author

Tailoring the interfaces of titanium with strontium and zinc: a surface functionalization approach with <i>in vitro</i> and <i>in vivo</i> evaluation for bone implants.

Biomaterials science·2025
Same author

Unveiling the Role of Zinc on the Nanotitania Network in Determining the <i>In Vitro</i> and <i>In Vivo</i> Characteristics of Titanium-Based Orthopedic Implants.

ACS applied materials & interfaces·2025
Same author

Polysaccharide-Based Self-Healing Hydrogel for pH-Induced Smart Release of Lauric Acid to Accelerate Wound Healing.

ACS applied bio materials·2025
Same journal

Electroactive Sodium Alginate-Based Hydrogel Textile for Synergistic Antibacterial and Regenerative Therapy in Diabetic Wound.

Advanced healthcare materials·2026
Same journal

Microfluidic Biofabrication of a Hydrogel Vessel-Like Structure for Interrogating Tumor Cell Propagation in a Breast Cancer-on-a-Chip Model.

Advanced healthcare materials·2026
Same journal

Hydrogel-Based Systems in Intrauterine Adhesions: Bridging the Gap from Bench to Bedside.

Advanced healthcare materials·2026
Same journal

A Muscle-Mimetic Core-Sheath Composite Yarn Scaffold for In-Body Tissue Induction and Regeneration of Small-Diameter Vascular Grafts.

Advanced healthcare materials·2026
Same journal

Gardiquimod Nanoemulsion Targets Cutaneous Leishmaniasis Lesions Reducing Systemic Toxicity and Parasite Burden.

Advanced healthcare materials·2026
Same journal

Therapeutic Extracellular Vesicles from Synovial Fibroblast-Primed MSCs for Osteoarthritis Treatment.

Advanced healthcare materials·2026
See all related articles

Related Experiment Video

Updated: Jan 10, 2026

Platelet-Derived Extracellular Vesicle Functionalization of Ti Implants
04:16

Platelet-Derived Extracellular Vesicle Functionalization of Ti Implants

Published on: August 5, 2021

2.7K

Magnesium and Zinc Co-Functionalized Nano-Structured Titania Surfaces Over Titanium Implants for Enhanced In Vitro

Sreya P1,2, Ann Mary Mathew1,2, Kalimuthu Vignesh3

  • 1Process Engineering Division, CSIR-Central Electrochemical Research Institute, Karaikudi, Tamil Nadu, India.

Advanced Healthcare Materials
|November 27, 2025
PubMed
Summary
This summary is machine-generated.

This study developed a novel Mg-Zn-functionalized nanotitania coating for titanium implants. This biomimetic interface enhances implant performance, showing improved antibacterial and bone-forming capabilities for biomedical applications.

Keywords:
In vitro compatibilityIn vivo osseointegrationMagnesium and ZincSurface‐functionalizationTitanium

More Related Videos

Fabrication of Mechanically Tunable and Bioactive Metal Scaffolds for Biomedical Applications
09:56

Fabrication of Mechanically Tunable and Bioactive Metal Scaffolds for Biomedical Applications

Published on: December 8, 2015

11.1K
Direct and Indirect Culture Methods for Studying Biodegradable Implant Materials In Vitro
14:49

Direct and Indirect Culture Methods for Studying Biodegradable Implant Materials In Vitro

Published on: April 15, 2022

5.6K

Related Experiment Videos

Last Updated: Jan 10, 2026

Platelet-Derived Extracellular Vesicle Functionalization of Ti Implants
04:16

Platelet-Derived Extracellular Vesicle Functionalization of Ti Implants

Published on: August 5, 2021

2.7K
Fabrication of Mechanically Tunable and Bioactive Metal Scaffolds for Biomedical Applications
09:56

Fabrication of Mechanically Tunable and Bioactive Metal Scaffolds for Biomedical Applications

Published on: December 8, 2015

11.1K
Direct and Indirect Culture Methods for Studying Biodegradable Implant Materials In Vitro
14:49

Direct and Indirect Culture Methods for Studying Biodegradable Implant Materials In Vitro

Published on: April 15, 2022

5.6K

Area of Science:

  • Biomaterials Science
  • Nanotechnology
  • Surface Chemistry

Background:

  • Titanium (Ti) implants are widely used in biomedical applications.
  • Enhancing the surface properties of Ti implants is crucial for improving biological performance and osseointegration.
  • Current methods often lack multifunctional capabilities for antibacterial and osteogenic enhancement.

Purpose of the Study:

  • To develop a biomimetic multifunctional nano-titania interface on Ti metal.
  • To co-functionalize the interface with Magnesium (Mg) and Zinc (Zn) ions.
  • To evaluate the improved surface and biological performance of the modified Ti implants.

Main Methods:

  • A simple chemical treatment approach was used for surface modification.
  • Characterization techniques included EDX, XPS, HR-TEM, AFM, water contact angle, and Raman spectroscopy.
  • Biological evaluations involved antibacterial assays, in vitro cell studies (MG-63 cells), and in vivo rat model studies.

Main Results:

  • The Mg-Zn-enriched surface demonstrated significant antibacterial activity against Staphylococcus aureus and Escherichia coli.
  • In vitro studies showed enhanced cell adhesion, viability, and mineralization, with no genotoxic stress.
  • In vivo studies on 3D printed Ti implants revealed improved osteogenesis and bone-to-implant contact.

Conclusions:

  • The developed Mg-Zn functionalized nanotitania network is a scalable approach.
  • This surface modification significantly improves the antibacterial and osteogenic properties of Ti implants.
  • The findings highlight the potential for enhanced performance of 3D-printed Ti implants in biomedical applications.