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Updated: Jan 10, 2026

Adjunctive Diode Laser Therapy and Probiotic Lactobacillus Therapy in the Treatment of Periodontitis and Peri-Implant Disease
Published on: May 9, 2022
Impact of low-level laser therapy on orthodontic pain
Sylwia Jagła1, Hanna Bielawska-Victorini2, Krzysztof Woźniak2
1Department of Maxillofacial Orthopaedics and Orthodontics, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University, Torun, Poland.
Introduction:
Pain is a primary deterrent to patient compliance in orthodontics. While pharmacological options exist, their systemic side effects warrant exploration of non-invasive alternatives. This study introduces Low-Level Laser Therapy (LLLT) as a localized, non-pharmacological intervention and evaluates its efficacy in mitigating pain during the critical initial phase of fixed appliance treatment.
Methods:
In this prospective controlled study, 60 patients (aged 14.6-37.1 years) were randomized into an LLLT group (n = 20) and a control group (n = 40). The LLLT group received daily photobiomodulation (670 nm, 4-6 J/cm2) for five consecutive days post-appliance placement. Pain was assessed daily using the Visual Analogue Scale (VAS), Laitinen Scale, and Verbal Rating Scale (VRS). Oral hygiene was evaluated using the Approximal Plaque Index (API).
Results:
LLLT significantly reduced pain perception. Pain peaked on day 2 for both groups, but the VAS score was lower in the LLLT group (4.35) than the control group (5.30). By day 4, the difference was highly significant (LLLT: 2.05 vs. Control:3.77; p < 0.0014). Furthermore, the LLLT group demonstrated significantly better oral hygiene, with a lower increase in API scores from T0 to T5 compared to the control group (p < 0.0003).
Conclusion And Application:
LLLT is an effective and safe modality for reducing acute orthodontic pain. Its localized action, absence of systemic side effects, and positive influence on oral hygiene make it available clinical tool for improving patient comfort and compliance during orthodontic therapy. This study provides strong evidence supporting the integration of LLLT into routine orthodontic practice.
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