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Experience in diagnosis and treatment of pediatric fibular osteomyelitis
Yuan Liang1, Zhenjiang Liu1, Xin Wang1
1Department of Orthopedics, Capital Center for Children's Health, Capital Medical University, Capital Institute of Pediatrics, Beijing, China.
Insights
Pediatric fibular osteomyelitis, often caused by Staphylococcus aureus, requires prompt diagnosis and treatment. Surgical intervention is frequently necessary, and while prognosis is generally good, recurrence can occur.
Area of Science:
- Pediatric Orthopedics
- Infectious Diseases
- Skeletal System Research
Background:
- Fibular osteomyelitis is a rare but serious bone infection in children.
- Diagnosis can be challenging due to insidious onset.
- Understanding clinical characteristics is vital for effective management.
Purpose of the Study:
- To analyze clinical features, diagnosis, treatment, and prognosis of pediatric fibular osteomyelitis.
- To identify factors influencing outcomes in rare pediatric osteomyelitis cases.
Main Methods:
- Retrospective analysis of clinical data from pediatric patients (2018-2024).
- Inclusion of demographic, clinical, laboratory, microbiological, and treatment data.
- Follow-up outcomes were assessed.
Main Results:
- 13 pediatric patients (median age 7.3 years) with fibular osteomyelitis were analyzed.
- Staphylococcus aureus was the most common pathogen (76.9% culture positivity), including MRSA.
- 11 of 13 patients required surgery; 3 experienced recurrence.
Conclusions:
- Pediatric fibular osteomyelitis presents diagnostic challenges.
- Staphylococcus aureus (including MRSA) is a key pathogen.
- Early diagnosis, appropriate antibiotics, and tailored surgery improve outcomes, though recurrence is possible.
Objective:
To summarize and analyze the clinical characteristics, diagnosis, treatment, and prognosis of pediatric fibular osteomyelitis, and to analyze related influencing factors, providing evidence for clinical management of pediatric osteomyelitis in rare locations.
Methods:
A retrospective analysis was conducted on the clinical data of pediatric patients with fibular osteomyelitis from January 2018 to December 2024, including demographic characteristics, clinical manifestations, laboratory and imaging examinations, microbiological results, treatment modalities, and follow-up outcomes.
Results:
A total of 13 patients were included (9 males, 4 females) with a median age of onset of 7.3 years. There were 11 acute cases and 2 chronic cases. The main clinical manifestations were bone pain, fever, and local abscess formation. The positive rate of microbiological culture was 76.9%, with Staphylococcus aureus being the most common pathogen (including 1 case of MRSA). Two patients responded effectively to antibiotic therapy alone, while 11 cases required surgical intervention, including fibular fenestration, debridement, segmental resection, and VSD therapy. All patients showed significant reduction in inflammatory markers after treatment. During 3-24 months of follow-up, 3 cases experienced recurrence requiring repeat surgery, with no severe disability or deformity observed.
Conclusion:
Pediatric fibular osteomyelitis has an insidious onset and poses diagnostic challenges. Staphylococcus aureus, particularly MRSA, represents the primary pathogen, with higher rates of surgical intervention and recurrence compared to other long bones. Early accurate diagnosis, adequate antibiotic therapy, and individualized surgical intervention are crucial for improving prognosis.
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