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Updated: Jan 10, 2026

Surgical Induction of Endolymphatic Hydrops by Obliteration of the Endolymphatic Duct
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Profound sensorineural hearing loss in ears with endolymphatic hydrops.

Tzu-Jui Lien1, Chun-Nan Chen1, Yu-Fen Wang2

  • 1Department of Otolaryngology, National Taiwan University Hospital, Taipei, Taiwan.

Acta Oto-Laryngologica
|November 27, 2025
PubMed
Summary

Endolymphatic hydrops (EH) can cause profound sensorineural hearing loss (SNHL). This may occur rapidly due to infection or develop slowly over years, indicating delayed EH.

Keywords:
Endolymphatic hydropsHydrops MRIMeniere’s diseaseprofound sensorineural hearing loss

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Area of Science:

  • Otolaryngology
  • Audiology
  • Radiology

Background:

  • Endolymphatic hydrops (EH) is increasingly identified via Hydrops MRI in patients with profound sensorineural hearing loss (SNHL).
  • This finding presents a discrepancy requiring investigation into the underlying mechanisms of SNHL in these cases.

Purpose of the Study:

  • To investigate the mechanisms behind profound SNHL in patients diagnosed with endolymphatic hydrops (EH).

Main Methods:

  • Evaluated 184 patients with Hydrops MRI, identifying 6 (3%) with profound SNHL.
  • Conducted comprehensive inner ear testing followed by Hydrops MRI for all affected patients.
  • Assessed the prevalence of EH in the cochlea and vestibule.

Main Results:

  • EH was present in the cochlea (67%) and vestibule (42%) of affected ears.
  • 50% of patients experienced rapid SNHL onset (1-2 months) in both ears, linked to superimposed infections.
  • The other 50% showed a delayed SNHL onset (5-8 years), attributed to the progression of EH.

Conclusions:

  • Profound SNHL in EH ears suggests two pathways: superimposed infection on pre-existing hydrops or delayed EH development.
  • Rapid onset implies infection exacerbating existing hydrops, while gradual onset indicates a slower progression of EH.