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The Patient Journey in Vitiligo.

Martina Turco1, Luigi Coronella2, Vincenzo Picone2

  • 1Section of Dermatology, Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy, martinaturco@me.com.

Dermatology (Basel, Switzerland)
|November 27, 2025
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Summary

Understanding the vitiligo patient journey is key to improving care. Early diagnosis, personalized treatment, and multidisciplinary support enhance quality of life for those with this chronic skin condition.

Keywords:
JourneyPatientVitiligo

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Area of Science:

  • Dermatology
  • Immunology
  • Genetics

Background:

  • Vitiligo is a chronic skin disorder causing depigmented macules due to melanocyte loss.
  • Its multifactorial pathogenesis involves autoimmune, genetic, and oxidative stress factors.
  • Delayed diagnosis and significant psychological impact affect patient quality of life.

Purpose of the Study:

  • To outline the typical patient journey for vitiligo.
  • To highlight challenges in diagnosis and treatment.
  • To emphasize the need for comprehensive, patient-centered care.

Main Methods:

  • Review of the vitiligo patient pathway from symptom onset to management.
  • Discussion of diagnostic tools (Wood's lamp, dermoscopy, biopsy).
  • Overview of current and emerging therapeutic strategies.

Main Results:

  • The patient journey often involves delayed diagnosis and psychological distress.
  • Disease severity assessment guides treatment selection.
  • Novel therapies like ruxolitinib cream offer targeted options.

Conclusions:

  • Optimizing the vitiligo patient journey requires structured care and early specialist involvement.
  • A multidisciplinary approach addressing clinical and psychosocial needs is crucial.
  • Healthcare systems must adapt for coordinated, patient-centered care with new treatments.