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EndoCompass Project: Research Roadmap for Reproductive and Developmental Endocrinology.

Martine Cools1,2, Csilla Krausz3,4, Anders Juul5,6

  • 1Department of Internal Medicine and Paediatrics, Ghent University, Ghent, Belgium.

Hormone Research in Paediatrics
|November 27, 2025
PubMed
Summary
This summary is machine-generated.

Endocrine research funding in Europe is insufficient. The EndoCompass project identified key priorities in reproductive and developmental endocrinology to guide future research and reduce disease burden.

Keywords:
EndoCompassFundingHypothalamic-pituitary-gonadal·axisReproductionRoadmap

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Area of Science:

  • Endocrinology
  • Reproductive Medicine
  • Developmental Biology

Background:

  • Endocrine science is underrepresented in EU research programs, despite hormone health's importance.
  • A gap exists between the societal impact of endocrine disorders and research funding prioritization.
  • National funding often overlooks endocrinology, prompting the EndoCompass project.

Purpose of the Study:

  • To identify and promote strategic research priorities in endocrine science.
  • To address critical hormone-related health challenges.
  • To align research funding with areas of high potential impact.

Main Methods:

  • Analysis of the EU CORDIS database (Horizon 2020).
  • Expert consultations to identify key research priorities.
  • Stakeholder engagement, including patient advocacy groups.

Main Results:

  • Priorities include variations in sex development and reproductive disorders.
  • Key areas: (epi)genetic diagnostics, optimized hormonal treatments, fertility preservation.
  • Emphasis on pan-European registries, reproductive technologies, and environmental impacts.

Conclusions:

  • Provides a roadmap for strategic research investment in endocrinology.
  • Identifies crucial areas in reproductive and developmental endocrinology.
  • Aims to reduce the burden of endocrine disorders on individuals and society.