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EndoCompass Project: Research Roadmap for Reproductive and Developmental Endocrinology
Martine Cools1,2, Csilla Krausz3,4, Anders Juul5,6
1Department of Internal Medicine and Paediatrics, Ghent University, Ghent, Belgium.
Hormone Research in Paediatrics
|November 27, 2025
Summary
Endocrine research funding in Europe is insufficient. The EndoCompass project identified key priorities in reproductive and developmental endocrinology to guide future research and reduce disease burden.
Area of Science:
- Endocrinology
- Reproductive Medicine
- Developmental Biology
Background:
- Endocrine science is underrepresented in EU research programs, despite hormone health's importance.
- A gap exists between the societal impact of endocrine disorders and research funding prioritization.
- National funding often overlooks endocrinology, prompting the EndoCompass project.
Purpose of the Study:
- To identify and promote strategic research priorities in endocrine science.
- To address critical hormone-related health challenges.
- To align research funding with areas of high potential impact.
Main Methods:
- Analysis of the EU CORDIS database (Horizon 2020).
- Expert consultations to identify key research priorities.
- Stakeholder engagement, including patient advocacy groups.
Main Results:
- Priorities include variations in sex development and reproductive disorders.
- Key areas: (epi)genetic diagnostics, optimized hormonal treatments, fertility preservation.
- Emphasis on pan-European registries, reproductive technologies, and environmental impacts.
Conclusions:
- Provides a roadmap for strategic research investment in endocrinology.
- Identifies crucial areas in reproductive and developmental endocrinology.
- Aims to reduce the burden of endocrine disorders on individuals and society.
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