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Related Concept Videos

The Endocrine System01:29

The Endocrine System

1.2K
The endocrine system is an extensive network of glands – organs or tissues in the body that create chemicals that control many bodily functions, that secrete hormones, which are chemical messengers that play essential roles in regulating various bodily functions. These hormones are secreted into the bloodstream and travel throughout the body. They require specific receptors to convey signals to cells possessing these corresponding receptors. This complex signaling mechanism ensures that...
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An Overview of the Endocrine System01:10

An Overview of the Endocrine System

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The endocrine system, a complex network of glands, orchestrates physiological balance within the body through the production and secretion of hormones. These hormones are chemical messengers in intercellular communication, acting as conduits between the secretory cells and distant target sites. They traverse the circulatory system by being released into the extracellular fluid, and their impact is specific to cells possessing receptors for a particular hormone.
The endocrine system collaborates...
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Structures of the Endocrine System00:59

Structures of the Endocrine System

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The intricate framework of the endocrine system encompasses a diverse array of glands, with their target tissues and organs strategically distributed throughout the body. Central to this network are the endocrine glands, specialized structures that lack ducts and release hormones directly into the interstitial fluid. Notably, the hypothalamus, a vital neuroendocrine organ situated in the brain, governs neural functions and serves as a potent source of hormonal regulation. Near the hypothalamus...
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Endocrine Signaling01:45

Endocrine Signaling

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Endocrine cells produce hormones to communicate with remote target cells found in other organs. The hormone reaches these distant areas using the circulatory system. This exposes the whole organism to the hormone but only those cells expressing hormone receptors or target cells are affected. Thus, endocrine signaling induces slow responses from its target cells but these effects also last longer.
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What is the Endocrine System?00:46

What is the Endocrine System?

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The endocrine system sends hormones—chemical signals—through the bloodstream to target cells—the cells the hormones selectively affect. These signals are produced in endocrine cells, secreted into the extracellular fluid, and then diffuse into the blood. Eventually, they diffuse out of the blood and bind to target cells which have specialized receptors to recognize the hormones.
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Hormonal Regulation01:40

Hormonal Regulation

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Hormones regulate a significant portion of digestion through activation of the neuroendocrine system. The neuroendocrine system of digestion contains many different hormones all with multiple functions that are both, directly and indirectly, involved in digestion.
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Postoperative changes in circulating brain injury biomarkers in relation to long-term fatigue and cognitive outcomes after surgery for nonfunctioning pituitary adenomas.

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Related Experiment Video

Updated: Jan 10, 2026

Author Spotlight: Insights into Cardiometabolic Diseases with Subcutaneous Adipose Tissue Microvasculature Studies
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EndoCompass Project: Endocrinology across the Lifespan.

Evelien F Gevers1,2, Martine Cools3,4, Anita C Hokken-Koelega5

  • 1Centre for Endocrinology, William Harvey Research Institute, Faculty of Medicine and Dentistry, Queen Mary University of London, London, UK, evelien.gevers@nhs.net.

Hormone Research in Paediatrics
|November 27, 2025
PubMed
Summary
This summary is machine-generated.

Endocrine science research needs strategic prioritization across all life stages, from conception to aging. The EndoCompass project identified key research areas to address hormone health challenges and Europe

Keywords:
AgingEndoCompassLifespanRoadmap

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Area of Science:

  • Endocrinology and hormone health research.
  • Lifespan approaches to endocrine science.
  • European research policy and funding.

Background:

  • Endocrine science is under-represented in European Union (EU) research programs.
  • A gap exists between the societal impact of endocrine disorders and research prioritization.
  • National funding often overlooks endocrinology, despite its importance.

Purpose of the Study:

  • To identify and promote strategic research priorities in endocrine science.
  • To address critical hormone-related health challenges.
  • To develop a roadmap for endocrine research across the lifespan.

Main Methods:

  • Analysis of the EU CORDIS database for Horizon 2020 (2014-2020).
  • Expert analysis of endocrine regulation and health from gametogenesis to aging.
  • Integration of evidence across developmental stages.

Main Results:

  • Key priorities include epigenetic programming, developmental origins of adult disease, brain-gut communication, and healthy aging.
  • Emphasis on critical developmental windows and transgenerational effects.
  • Need for integrated research spanning pediatric and adult endocrinology.

Conclusions:

  • Provides an evidence-based roadmap for hormone regulation across life stages.
  • Highlights the need for coordinated, lifespan research to address demographic challenges.
  • Supports strategic investment in comprehensive endocrine health approaches.