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Human fear responses to certain stimuli, such as darkness, heights, deep water, and blood, can often arise despite the absence of direct negative experiences. This phenomenon is rooted in evolutionary psychology, which posits that humans have developed a predisposition to fear stimuli that historically posed significant survival threats. This predisposition, known as preparedness, suggests that early humans who developed a fear of potentially dangerous entities, such as venomous snakes and...
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Social anxiety disorder, also known as social phobia, is characterized by an intense fear of social situations where one might face humiliation, rejection, embarrassment, or negative evaluation. This disorder leads individuals to avoid activities like casual conversations, public speaking, or seemingly simple tasks such as eating, signing documents, or swimming, in public settings. Its impact extends beyond discomfort, often significantly interfering with daily functioning and quality of life.
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Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing  genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
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Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information
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Basophobia: A case report highlighting potential genetic vulnerability.

Jawahar Singh1, Mahak Aggarwal1, Pratiksha Bugalia1

  • 1All India Institute of Medical Sciences (AIIMS), Bathinda, Punjab, India.

Asian Journal of Psychiatry
|November 27, 2025
PubMed
Summary

Basophobia, a rare fear of falling in open spaces, may run in families. This case study is the first to document familial aggregation of basophobia, suggesting a potential genetic link.

Area of Science:

  • Psychiatry
  • Neuroscience
  • Genetics

Background:

  • Basophobia (space phobia) is a specific phobia involving fear of falling in open spaces.
  • Familial aggregation is known in specific phobias, but not previously reported for basophobia.
Keywords:
BasophobiaFear of fallingGenetic predispositionSpecific phobia

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