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Factors Associated With Demoralization in Patients With Parkinson's Disease
Wei-Ting Chien1, Yu Lee1, Yung-Yee Chang2
1Department of Psychiatry, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Journal of the Academy of Consultation-Liaison Psychiatry
|November 27, 2025
Summary
Demoralization in Parkinson's disease patients is linked to their own and their caregivers' anxiety and depression. Addressing these factors can improve patient quality of life.
Area of Science:
- Neuroscience
- Psychiatry
- Gerontology
Background:
- Parkinson's disease (PD) is a progressive neurodegenerative disorder affecting adults.
- Demoralization is characterized by hopelessness, helplessness, and existential distress.
Purpose of the Study:
- To identify factors associated with demoralization in patients with Parkinson's disease.
Main Methods:
- Cross-sectional study of 120 Parkinson's disease patients and caregivers in Taiwan.
- Psychological well-being assessed using Demoralization Scale (DS), HADS-D, HADS-A, BFI, and EMIC.
Main Results:
- Higher patient depression and anxiety, and higher caregiver anxiety, were linked to patient demoralization.
- Patient depression severity correlated with patient and caregiver anxiety.
- Patient and caregiver anxiety significantly predicted demoralization severity in Parkinson's disease patients.
Conclusions:
- Early identification and management of depression and anxiety are crucial for PD patients.
- Addressing these factors can mitigate existential distress and improve coping.
- Interventions targeting patient and caregiver mental health may enhance quality of life in Parkinson's disease.
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