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CHD8 -Related Neurodevelopmental Disorder Manifesting Adult-Onset Compulsive Behaviors
Shih-Chun Lan1, Min-Yu Lan2,3,4, Yung-Yee Chang2,3
1School of Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.
Abstract:
A patient of intellectual developmental disorder with autism and macrocephaly (IDDAM) caused by a novel CHD8 mutation developed adult-onset compulsive behaviors in addition to the core phenotype in early life. This case expands the clinical and genotypic spectrums of IDDAM which may inspire future studies on genotype-phenotype correlation and the disease course.
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