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Project Psyche: reference genomes for all Lepidoptera in Europe.
Charlotte J Wright1, Niklas Wahlberg2, Roger Vila3
1Tree of Life Programme, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire, CB10 1SA, United Kingdom.
Project Psyche is generating chromosome-level reference genomes for European butterflies and moths (Lepidoptera). This biodiversity genomics initiative provides an open-access dataset to advance evolutionary and ecological research.
Area of Science:
- Genomics
- Evolutionary Biology
- Ecology
- Conservation Biology
Background:
- The Lepidoptera order, comprising butterflies and moths, represents a significant portion of European biodiversity.
- Understanding the genomic landscape of Lepidoptera is crucial for ecological and evolutionary studies.
Purpose of the Study:
- To establish a comprehensive, chromosome-level reference genome dataset for all ~11,000 European Lepidoptera species.
- To create a decentralized network for efficient genome generation and data analysis.
Main Methods:
- Implementing standardized protocols for sample collection, DNA extraction, and high-throughput sequencing.
- Establishing a collaborative framework involving multiple international hubs for data generation and analysis.
- Utilizing advanced sequencing technologies to achieve chromosome-level genome assemblies.
Main Results:
- Over 1000 Lepidoptera species have already been sequenced, positioning the order at the forefront of biodiversity genomics.
- Development of a decentralized network of collection and sequencing hubs enabling rapid project progress.
- Creation of standardized protocols for sampling, sequencing, and data analysis.
Conclusions:
- The open-access Lepidoptera genome catalogue will significantly enhance understanding of evolutionary and ecological processes.
- This genomic resource will be invaluable for informing conservation strategies and managing pest and invasive species.
- The project highlights the potential of large-scale biodiversity genomics initiatives to drive scientific discovery.
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