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Bio-Inspired Micro-Fin-Assisted Multi-Modal Vascular Intervention.

Xu Liu1, Qiang Luo2, Zhuoqun Cao1

  • 1Department of Mechanical and Aerospace Engineering, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, Kowloon, P. R. China.

Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
|November 27, 2025
PubMed
Summary
This summary is machine-generated.

New magnetic guidewires with micro-fins enhance vascular navigation. This innovation improves steerability in complex anatomy, reducing procedure time and enabling safer interventions in vascular medicine.

Keywords:
flow‐asistedmagnetic micro‐fins‐integrated tipmulti‐modalvascular intervention

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Area of Science:

  • Medical Devices
  • Biomedical Engineering
  • Vascular Surgery

Background:

  • Precise navigation in vascular medicine is challenging due to guidewire limitations in tortuous anatomy.
  • Existing magnetic guidewires require bulky external magnetic field control systems, limiting their use in confined interventional rooms.

Purpose of the Study:

  • To introduce a novel magnetic guidewire with a micro-fin-integrated tip for enhanced multimodal vascular intervention.
  • To improve guidewire control, efficiency, and maneuverability in complex vascular environments.

Main Methods:

  • Development of a magnetic guidewire featuring a micro-fin-integrated tip.
  • Utilizing micro-fins to generate additional torques via fluid drag and vessel wall contact, supplementing magnetic forces.
  • In vivo testing in rabbit vascular models to evaluate performance compared to commercial guidewires.

Main Results:

  • The micro-fin guidewire successfully navigated bifurcations using lower magnetic field strength (15 mT compared to 34 mT).
  • The device demonstrated tolerance to external field misalignments up to 45 degrees.
  • In vivo tests showed a ≈50% reduction in procedure time and rapid access to major arteries.

Conclusions:

  • Micro-fin integration significantly enhances the control and efficiency of magnetic guidewires.
  • This technology offers improved steerability and maneuverability for interventional procedures in complex vasculature.
  • The novel design overcomes limitations of conventional magnetic guidewires, paving the way for safer and faster vascular interventions.