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Related Experiment Video

Updated: Jan 10, 2026

Ookluc: A Plasmodium berghei Line for Identifying Transmission-blocking Compounds

Ookluc: A Plasmodium berghei Line for Identifying Transmission-blocking Compounds

Published on: July 11, 2025

Plasmodium knowlesi and global changes: socio-ecological drivers and challenges.

Fauzi Muh¹, Nabila Gusvie Qanita², Mutiara Rizqi Yuwanita³

¹Department of Epidemiology and Tropical Diseases, Faculty of Public Health, Universitas Diponegoro, Semarang, 50275, Indonesia. fauzimuh010@gmail.com.

Malaria Journal

|November 28, 2025

Summary

Climate change impacts Plasmodium knowlesi malaria transmission by altering mosquito behavior and host distribution. Understanding these complex interactions is key to controlling its spread, especially in Southeast Asia.

Keywords:

P. knowlesi Climate change Malaria Zoonosis

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Area of Science:

Environmental Science
Epidemiology
Parasitology

Background:

Plasmodium knowlesi malaria is a significant public health concern in Southeast Asia.
Climate change is increasingly recognized as a driver of infectious disease dynamics.

Purpose of the Study:

To review the multifaceted impact of climate change on Plasmodium knowlesi transmission.
To explore the interplay between climate, land use, host-vector interactions, and human behavior.

Main Methods:

Literature review synthesizing existing research on Plasmodium knowlesi and climate change.
Analysis of environmental factors influencing parasite, vector, and host dynamics.
Examination of human behavior and community responses to environmental shifts.

Main Results:

Climate variations (temperature, precipitation) directly affect mosquito vectors and parasite development.
Deforestation and land-use changes driven by climate change facilitate zoonotic transmission.
Human behavior and the attitude-behavior gap present challenges in disease control.

Conclusions:

Climate change profoundly influences Plasmodium knowlesi transmission through ecological and behavioral pathways.
Integrated strategies addressing environmental, ecological, and social factors are essential for control.
Further research is needed to manage P. knowlesi in regions with increasing human-animal-vector interactions.