A massive ocular surface squamous cell carcinoma: a case report

Squamous cell carcinoma of the conjunctiva is a rare local malignancy, and there are few reports in literature of massive growth within 7 weeks.

A 60-year old Yemeni male, complained from heaviness discomfort with 2 weeks fresh bleeding from left orbital big mass. The tumor spell out the entire orbital outlet as pinkish fleshy fine lobes in tumor sides as most of the upper and lower surface was covered by intact skin. There was a history of eye-surface growth excision followed by lids closure 18 months back. The magnetic resonance imaging showed the tumor dimensions (10.8 × 9.8 × 9.4 cm) with the eye in its posterior part. The patient underwent urgent de-bulking by exentration (hemoglobin was 7.0 gm%) with adjuvant radiation after a histopathology diagnosis of well-differentiated squamous cell carcinoma. The low socioeconomic status and other unknown factors might enhance the tumor (rapid) growth. The patient was healthy for 17 months post management, thereafter got left leg limping. By 24 months, the magnetic resonance imaging with angiography of the whole body showed: irregular lesion in upper temporal part of the left orbit and 9 × 4 × 2 cm mass within the left calf muscle and 2.5 × 2.2 cm and 2 × 1.7 cm in diameters in left and right lungs.

This is a rapidly growing with massive size ocular surface squamous cell carcinoma exhibited was also recurrent exhibited systemic manifestations within 4 years of onset, although initially it was isolated and low staging.