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Progressive vestibular dysfunction in unilateral acute otitis media with serous labyrinthitis: a case report
Liqing Chen1,2, Yunwen Wu1, Yan Li1
1Department of Otolaryngology, Head and Neck Surgery, Shenzhen University General Hospital, Shenzhen, 518055, China.
Journal of Medical Case Reports
|November 28, 2025
Summary
Serous labyrinthitis, an inner ear inflammation often linked to acute otitis media, can cause significant vertigo. Early antibiotic and glucocorticoid treatment effectively restored vestibular function in a case study.
Area of Science:
- Otolaryngology
- Neuroscience
- Inner Ear Physiology
Background:
- Serous labyrinthitis is an inner ear inflammation often secondary to acute otitis media.
- It can lead to progressive vestibular dysfunction, including vertigo and nystagmus.
- Understanding the mechanisms is crucial for effective management.
Purpose of the Study:
- To investigate changes in vestibular function in serous labyrinthitis.
- To explore the underlying mechanisms of vestibular dysfunction in this condition.
- To evaluate the efficacy of combined antibiotic and glucocorticoid therapy.
Main Methods:
- A case study of a 34-year-old female with serous labyrinthitis secondary to acute otitis media.
- Treatment involved intravenous ceftriaxone sodium and dexamethasone, plus nasal sprays.
- Audiological and vestibular function assessments were performed.
Main Results:
- The patient experienced progressive vestibular dysfunction.
- Within one week of treatment, audiometric thresholds normalized.
- Nystagmus intensity decreased, and vertigo resolved completely.
Conclusions:
- Unidirectional irritative nystagmus is a key sign of labyrinthitis secondary to otitis media.
- Integrated audiological and vestibular assessments are vital to prevent diagnostic delays.
- Early combination therapy with antibiotics and glucocorticoids appears highly effective.
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