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Area of Science:

  • Oncology
  • Cancer Survivorship Research
  • Neuro-oncology

Background:

  • Cancer is a major global health issue with millions of new cases annually.
  • Advances in cancer prevention and treatment are increasing survival rates.
  • Cognitive dysfunction is a prevalent symptom impacting cancer survivors' quality of life.

Purpose of the Study:

  • To provide a comprehensive overview of cancer epidemiology, risk factors, and biology.
  • To discuss mechanisms and side effects of various cancer therapies.
  • To review central nervous system tumors and treatment considerations.

Main Methods:

  • Literature review and synthesis of existing research.
  • Overview of cancer incidence, mortality, and survival trends.
  • Discussion of therapeutic modalities and their associated toxicities.

Main Results:

  • Cancer mortality is declining due to progress in care.
  • Cognitive dysfunction is a significant long-term symptom for survivors.
  • Understanding of cancer biology and treatment side effects is advancing.

Conclusions:

  • Continued research is essential for managing cancer-related cognitive dysfunction.
  • Improved supportive care and symptom management are crucial for cancer survivors.
  • This review serves as a foundation for further investigation into cancer survivorship challenges.