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Related Concept Videos

Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

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Related Experiment Video

Updated: May 7, 2026

A 3D Organotypic Melanoma Spheroid Skin Model
08:49

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Recurrent melanoma presenting as a rash: a case report.

Annabelle Huntsman1, Katherine Gillis1, Anneli R Bowen2

  • 1School of Medicine, University of Utah, Salt Lake City, UT, USA.

Skin Health and Disease
|November 28, 2025
PubMed
Summary
This summary is machine-generated.

This case study details an unusual presentation of melanoma recurrence in a patient undergoing talimogene laherparepvec (T-VEC) therapy. Early biopsy is crucial for diagnosing new skin findings in melanoma patients.

Area of Science:

  • Oncology
  • Dermatology
  • Cancer Research

Background:

  • Melanoma is an aggressive skin cancer.
  • Recurrence, though rare, often presents as pigmented lesions near the primary site.

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  • Intralesional talimogene laherparepvec (T-VEC) is a therapy used for melanoma.