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Updated: Jan 10, 2026

Generation and Expansion of Primary, Malignant Pleural Mesothelioma Tumor Lines
Published on: April 21, 2022
Case Report: Whispers of the serpent: exploring uncommon imaging features in primary hepatic malignant mesothelioma
Guoan Li1, Shengqian Hong1, Tao He1
1The Affiliated Huaian No.1 People's Hospital of Nanjing Medical University, Huai'an, China.
Abstract:
Primary hepatic malignant mesothelioma (PHMM) is an uncommon and aggressive neoplasm with vague clinical and radiological features, posing challenges for preoperative diagnosis. In our case, a lobulated hepatic mass demonstrated a serpiginous peripheral enhancement pattern on contrast-enhanced CT and MRI. This uncommon imaging manifestation has been sporadically documented in previous reports. By consolidating these findings, our report emphasizes serpiginous peripheral enhancement as a potential diagnostic clue for PHMM. Recognition of this pattern may aid earlier detection, improve differential diagnosis, and guide timely surgical decision-making in affected patients.
Insights
Primary hepatic malignant mesothelioma (PHMM) is a rare liver cancer. A distinctive serpiginous peripheral enhancement pattern on imaging may help in its early diagnosis and treatment.
Area of Science:
- Hepatology
- Oncology
- Radiology
Background:
- Primary hepatic malignant mesothelioma (PHMM) is a rare and aggressive liver neoplasm.
- PHMM presents with nonspecific clinical and radiological features, complicating preoperative diagnosis.

