Recent Progress in Green Sample Preparation for Improved Plant-Based Natural Product and Phenolic Compound Analysis.

Area of Science:

• Plant Metabolism
• Phytochemistry
• Analytical Chemistry

Background:

• Phenolic compounds are vital plant secondary metabolites with diverse roles and health benefits.
• Their extraction is crucial for study, influenced by various factors like method and solvent.
• Sustainable extraction from food waste is gaining importance.

Purpose of the Study:

• To provide a comprehensive overview of green sample preparation (GSP) techniques for phenolic compounds.
• To highlight strategies minimizing environmental impact in analytical chemistry.
• To discuss optimization methods and greenness assessment tools for GSP.

Main Methods:

• Review of conventional and innovative extraction methodologies, focusing on green technologies.
• Emphasis on micro-techniques, assisted extraction, and eco-friendly solvents.
• Discussion of experimental design for yield optimization and greenness assessment tools.

Main Results:

• Advancements in GSP techniques within green analytical chemistry (GAC) are presented.
• Strategies for minimizing environmental impact, including micro-techniques and eco-friendly solvents, are highlighted.
• Methods for optimizing phenolic compound yields and assessing the greenness of techniques are discussed.

Conclusions:

• Green sample preparation techniques are crucial for sustainable analysis of phenolic compounds.
• Adoption of GSP minimizes environmental impact and enhances operational efficiency.
• Further development and application of GSP tools are essential for advancing green analytical chemistry.