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Published on: July 13, 2019
Evaluation of the effectiveness of solutions for clearing neonatal central venous catheters: randomized study
Carolina Mathiolli1, Juliane Pagliari Araujo2, Keli Regiane Tomeleri da Fonseca Pinto1
1Universidade Estadual de Londrina, Departamento de Enfermagem, Londrina, PR, Brazil.
Objective:
To evaluate the effectiveness of saline, heparin, and vitamin C solutions in unclogging neonatal central venous catheters occluded by clots.
Method:
A randomized, double-blind, in vitro experimental study conducted in August 2022 with 90 neonatal central venous catheters occluded with blood that remained in a water bath for 8 hours. The solutions tested were: saline, heparin (50 mg/ml), and vitamin C (25 mg/ml), using a negative pressure technique. The variables of number of attempts and time to unclogging were evaluated in relation to the mean and standard deviation. For variables with abnormal distribution, the Kruskal-Wallis test was used.
Results:
There was no statistical significance in relation to the time and number of attempts to unclog the three solutions (p > 0.05), and the maximum time to unclog the catheters was 120 minutes.
Conclusion:
The three substances showed similar results. Thus, saline solution is recommended because it is considered safe, with fewer side effects when used in newborns.
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