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Melioidosis imported to Northern Germany: a case report series

Dorothea Ekoka Mbassi1,2,3, Aiman Gamal Abdelrahim4,5, Ilka Grewe4,6,7

  • 1Department of Medicine, Gastroenterology, Infectious Diseases and Tropical Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. d.ekokambassi@uke.de.

Infection
|November 28, 2025
PubMed
Abstract

Insights

Melioidosis, a severe infection caused by Burkholderia pseudomallei, presents diverse symptoms in travellers. Early consideration and prolonged antibiotic therapy are crucial for managing this potentially fatal disease.

Area of Science:

  • Infectious Diseases
  • Tropical Medicine
  • Microbiology

Background:

  • Melioidosis is a significant infection caused by Burkholderia pseudomallei, prevalent in tropical and subtropical environments.
  • The bacterium resides in soil, water, and plants, posing a risk in endemic regions.
  • Infection can lead to severe illness and mortality if not treated promptly.

Purpose of the Study:

  • To highlight the varied clinical presentations of melioidosis.
  • To emphasize the importance of considering melioidosis in returning travelers.
  • To discuss therapeutic strategies for melioidosis.

Main Methods:

  • Case report of four tourists diagnosed with melioidosis.
  • Review of clinical manifestations and treatment approaches.
  • Analysis of diagnostic challenges due to diverse symptoms.

Main Results:

  • The four cases demonstrated a wide range of clinical symptoms, including respiratory issues and multiple organ abscesses.
  • Diverse presentations such as fever, night sweats, weight loss, dyspnea, and abscesses were observed.
  • Successful treatment involved prolonged antibiotic courses.

Conclusions:

  • Melioidosis exhibits variable clinical features, complicating diagnosis.
  • Healthcare providers should consider melioidosis in travelers from endemic areas with compatible symptoms.
  • Extended antibiotic treatment is vital for successful recovery from melioidosis.
Keywords:
Burkholderia pseudomalleiCase seriesImported infectious diseasesMelioidosis

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