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Updated: Jan 10, 2026

Modeling Ascending Vaginal Infection, Preterm Birth, and Neonatal Morbidity in Mice
Published on: October 10, 2025
Infectious morbidity associated with early amniotomy during labor induction.
Corina N Schoen1, Elizabeth Baker2, Ravneet Thind2
1Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, UMASS Chan Medical School - Baystate, Springfield, MA 01199, USA.
Performing amniotomy less than 12 hours after cervical ripening initiation does not increase maternal or neonatal infectious morbidity. Early amniotomy is associated with reduced infectious complications, shorter labor, and lower cesarean rates.
Area of Science:
- Obstetrics and Gynecology
- Maternal-Fetal Medicine
- Reproductive Health
Background:
- Cervical ripening is a common intervention in labor induction.
- The timing of artificial rupture of membranes (AROM) during labor induction is debated.
- Potential risks include infectious morbidity and prolonged labor.
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