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Updated: Jan 10, 2026

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Raspberry polysaccharide extraction, purification, structural characterization, and biological activity research

Fangyao Zhao1, Junhao Li1, Jian Yang2

  • 1College of Life Sciences, China Jiliang University, Hangzhou, 310018, China.

International Journal of Biological Macromolecules
|November 28, 2025
PubMed
Summary

Raspberry polysaccharides show promising health benefits like anti-inflammatory and antioxidant effects. Understanding their structure, influenced by extraction methods, is key to unlocking their full potential in functional foods and pharmaceuticals.

Keywords:
Application prospectsBiological activityExtraction and purificationRaspberry polysaccharidesStructural characterization

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Area of Science:

  • Phytochemistry
  • Pharmacology
  • Food Science

Background:

  • Raspberry (Rubus idaeus L.) polysaccharides possess significant medicinal and edible value.
  • These compounds exhibit potent biological activities, including anti-inflammatory, antioxidant, antitumor, and immunomodulatory effects.
  • The bioefficacy of raspberry polysaccharides is critically dependent on their fine structures, influenced by extraction and purification methods.

Purpose of the Study:

  • To provide a comprehensive review of current research on raspberry polysaccharides.
  • To elucidate the intricate process-structure-activity relationship for effective utilization.
  • To establish a scientific framework for translating research from lab-scale to industrial production.

Main Methods:

  • Systematic synthesis of current research on extraction and purification techniques.
  • Review of methods for structural characterization of polysaccharides.
  • Analysis of underlying mechanisms of biological activity and potential applications.

Main Results:

  • Extraction and purification methodologies significantly dictate the fine structures of raspberry polysaccharides.
  • Structural variations directly impact the observed biological activities.
  • Advanced techniques are crucial for optimizing polysaccharide properties.

Conclusions:

  • Elucidating the process-structure-activity relationship is paramount for raspberry polysaccharide utilization.
  • Further research can facilitate the development of raspberry polysaccharides for functional foods and pharmaceuticals.
  • A robust scientific framework is needed for industrial-scale production.