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Updated: Jan 10, 2026
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Critical considerations in shock index application for normotensive trauma patients: Limitations and future
Siffat Ullah1, Abdullah Muhammad Abu Bakar2, Hussain Ramzan3
1Nanchang university china.
None:
This letter addresses the research conducted by Lin et al. regarding the shock index (SI) as an indicator of compensated shock in normotensive trauma cases. We acknowledge the authors' efforts while highlighting significant limitations: overlooked confounding due to cardioactive drugs, survival bias from omitting early fatalities, influences of prehospital fluid resuscitation, and insufficient age-specific SI thresholds. We additionally challenge transfusion as a surrogate for shock and emphasize the variation in injury mechanisms. Suggestions consist of modifications in pharmacovigilance, incorporation of early mortality statistics, and multi-center confirmations with microcirculatory outcomes.
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