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Updated: Jan 10, 2026

A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators
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A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators

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Class A and B GPCRs trigger rapid Gαs translocation to late and slow recycling endosomes

Andréanne Laniel1, Brian Holleran1, Émy Labonté1

  • 1Institut de Pharmacologie de Sherbrooke, Department of Pharmacology and Physiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Quebec, QC, Canada.

Communications Biology
|November 29, 2025
PubMed

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