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Related Concept Videos

Mitral Valve Prolapse I: Introduction01:27

Mitral Valve Prolapse I: Introduction

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IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...
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Mitral Valve Prolapse II: Assessment and Management01:22

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IntroductionA range of clinical features characterizes Mitral Valve Prolapse (MVP), but it is important to note that many individuals with MVP are asymptomatic and may remain so throughout their lives. For those who do exhibit symptoms, the following are the key clinical features:Palpitations: This is a common symptom where individuals feel an irregular or rapid heartbeat. Palpitations in MVP are often due to arrhythmias such as premature ventricular contractions or supraventricular...
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Pericarditis II: Clinical Features and Diagnostic Tests01:19

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Pericarditis is distinguished by inflammation of the pericardium, the fibrous sac that encases the heart. It can be acute, lasting less than six weeks, or chronic, persisting for over three months. Understanding its clinical manifestations and diagnostic findings is crucial for timely and effective management.Clinical ManifestationsWhile pericarditis can be asymptomatic, it usually presents with characteristic symptoms such as:Chest Pain: The most characteristic symptom of pericarditis is chest...
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Related Experiment Video

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Development of a Rabbit Chronic-Like Rotator Cuff Injury Model for Study of Fibrosis and Muscular Fatty Degeneration
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Chronic papillary muscle rupture, a case report.

Napat Pruekprasert1, McKenna Schimmel2, Aaron Lambert3

  • 1Department of Surgery, SUNY Upstate Medical University, 750 E Adams St #814, Syracuse, 13210, NY, USA.

Journal of Cardiothoracic Surgery
|November 29, 2025
PubMed
Summary

This case study presents a rare instance of chronic mitral regurgitation caused by papillary muscle rupture, a condition typically acute. Early diagnosis via echocardiography and surgical intervention led to a successful recovery.

Keywords:
Chronic mitral regurgitationMitral valve replacementPapillary muscle rupture

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Area of Science:

  • Cardiology
  • Cardiac Surgery
  • Echocardiography

Background:

  • Papillary muscle rupture is a rare but life-threatening complication of acute myocardial ischemia.
  • It usually leads to acute severe mitral regurgitation and cardiogenic shock, necessitating urgent intervention.
  • Chronic presentation is highly unusual, with limited reported cases.

Purpose of the Study:

  • To report a rare case of chronic mitral regurgitation secondary to papillary muscle rupture.
  • To highlight the diagnostic challenges and successful management of such a case.
  • To emphasize the importance of echocardiography in diagnosing this condition.

Main Methods:

  • A 70-year-old female presented with several months of fatigue and dyspnea.
  • Diagnostic echocardiography revealed severe mitral regurgitation with posterior mitral leaflet prolapse.
  • Cardiac catheterization identified significant coronary artery stenosis, leading to bioprosthetic mitral valve replacement and coronary bypass surgery.

Main Results:

  • The patient was diagnosed with severe mitral regurgitation due to suspected papillary muscle rupture.
  • Surgical intervention included mitral valve replacement and coronary artery bypass grafting.
  • The patient experienced an uneventful recovery and became symptom-free.

Conclusions:

  • Chronic presentation of mitral regurgitation from papillary muscle rupture is rare but possible, manifesting as progressive symptoms.
  • High index of suspicion and careful echocardiographic examination are crucial for diagnosis.
  • Mitral valve replacement is a common surgical solution, with repair or percutaneous interventions as alternatives for select patients.