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Published on: April 8, 2013
Is Surgical Ventricular Restoration Still Relevant in Ischaemic Heart Failure Treatment? A 20-Year Follow-up Study
Huajun Zhang1,2, Changqing Gao1, Cangsong Xiao2
1Department of Cardiovascular Surgery, The First Medical Center of Chinese PLA General Hospital.
Objectives:
As new technologies are being developed to treat ischaemic heart failure, the relevance of surgical ventricular restoration (SVR) is unclear. Our aim was to determine the long-term surgical and echocardiographic outcomes of SVR for up to 20 years postoperatively.
Methods:
From April 1997 to December 2019, a total of 128 patients with ischaemic heart failure underwent SVR at our institution. Concomitant surgical revascularization was performed wherever possible. The patients were tracked for up to 20 years by correspondence, in outpatient clinics or through hospitalization, with an echocardiographic evaluation performed when appropriate.
Results:
The average age at the time of the operation was 57 ± 10 years (range: 33-79), and 92% of the patients were male. Anterior-septal aneurysms were observed in 88.9% of the patients, and 11.1% had inferior aneurysms. The medians and interquartile ranges of the preoperative left ventricular ejection fraction, end-systolic volume index, and the end-diastolic volume index were 37% (3%, 43%), 60.7 (48.4, 73.3) mL/m2, and 93.9 (79.3, 112.3) mL/m2. The operative mortality rate was 3.1% (4/128). The postoperative left ventricular ejection fraction was 46% (43%, 50%), the end-systolic volume index was 30.4 (26.9, 37.6) mL/m2, and the end-diastolic volume index was 56.4 (48.4, 67.5) mL/m2. The 5-, 10-, and 20-year survival rates and their 95% confidence intervals were 91.27% (86.46%, 96.34%), 75.76% (67.6%, 84.92%), and 20.91% (9.17%, 47.66%), respectively.
Conclusions:
SVR was associated with excellent long-term survival and a significant improvement in left ventricular function. Therefore, it continues to play an important role, even in this new era of treatment for ischaemic heart failure.
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