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Feedback Inhibition00:46

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Biochemical reactions are occurring constantly in cells, converting starting substances to different products, usually with the help of enzymes that speed the reactions. Without enzymes, it would take far too long for most reactions to occur to be useful to the cell!
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Synthesis of new DNA molecules is carried out by the enzyme DNA polymerase, which adds nucleotides on the daughter strand complementary to the template DNA strand. DNA polymerase has a higher affinity to add the correct base and ensures fidelity during DNA replication. Furthermore,  it exhibits proofreading activity during replication, using an exonuclease domain that cuts off incorrect nucleotides from the nascent DNA strand.
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Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
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Author's reply

Diego Raimondo1, Linda Bertoldo2, Matteo Giorgi3

  • 1Division of Gynecology and Human Reproduction Physiopathology, IRCCS Azienda Ospedaliero Universitaria, 40138 Bologna, Italy.

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