Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Next-generation Sequencing03:00

Next-generation Sequencing

97.6K
The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features....
97.6K
Plant Breeding and Biotechnology01:59

Plant Breeding and Biotechnology

21.4K
Crop cultivation has a long history in human civilization, with records showing the cultivation of cereal plants beginning at around 8000 BC. This early plant breeding was developed primarily to provide a steady supply of food.
21.4K
Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

15.2K
Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
15.2K
Genomics02:02

Genomics

39.6K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
39.6K
Sanger Sequencing01:57

Sanger Sequencing

772.9K
DNA sequencing is a fundamental technique that is routinely used in the biological sciences. This method can be applied to a range of questions at different scales - from the sequencing of a cloned DNA fragment or the study of a mutation in a gene up to whole-genome sequencing. However, despite the widespread use of sequencing today, it was not until 1977 that Fredrick Sanger and his collaborators developed the chain-termination method to decode DNA sequences. It relies on the separation of a...
772.9K
Maxam-Gilbert Sequencing01:05

Maxam-Gilbert Sequencing

12.5K
In the same year as the discovery of the Sanger sequencing method, another group of scientists, Allan Maxam and Walter Gilbert, demonstrated their chemical-cleavage method for DNA sequencing. The Maxam-Gilbert method relies on using different chemicals that can cleave the DNA sequence at specific sites, the separation of resulting DNA fragments of variable size using electrophoresis, and deciphering the DNA sequence from the resulting gel bands.
Challenges of the Maxam-Gilbert Method
The...
12.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Multi-locus GWAS to unravel the genetic architecture of grain iron, zinc and protein contents in wheat (Triticum aestivum L.) genotypes evaluated over multiple locations and years.

BMC plant biology·2026
Same author

Ensemble of Bayesian alphabets via constraint weight optimization strategy improves genomic prediction accuracy.

G3 (Bethesda, Md.)·2025
Same author

Identification and characterization of sulphotransferase (SOT) genes for tolerance against drought and heat in wheat and six related species.

Molecular biology reports·2024
Same author

Mapping of QTLs and meta-QTLs for Heterodera avenae Woll. resistance in common wheat (Triticum aestivum L.).

BMC plant biology·2023
Same author

Candidate effectors for leaf rust resistance gene <i>Lr28</i> identified through transcriptome and <i>in-silico</i> analysis.

Frontiers in microbiology·2023
Same author

Identification and characterization of RuvBL DNA helicase genes for tolerance against abiotic stresses in bread wheat (Triticum aestivum L.) and related species.

Functional & integrative genomics·2023

Related Experiment Video

Updated: Jan 9, 2026

Development of Targeting Induced Local Lesions IN Genomes TILLING Populations in Small Grain Crops by Ethyl Methanesulfonate Mutagenesis
08:36

Development of Targeting Induced Local Lesions IN Genomes TILLING Populations in Small Grain Crops by Ethyl Methanesulfonate Mutagenesis

Published on: July 16, 2019

12.2K

Twenty years of wheat genomics (2005-2025).

Pushpendra Kumar Gupta1

  • 1Department of Genetics and Plant Breeding, CCS University, Meerut, UP 250004, India.

Trends in Plant Science
|November 29, 2025
PubMed
Summary

Global wheat genomics efforts culminated in 2025 with complete genome sequences. This breakthrough resource will accelerate the improvement of this vital global crop.

Area of Science:

  • Plant genomics
  • Crop science
  • Agricultural biotechnology

Background:

  • Wheat is a globally significant staple crop, crucial for food security.
  • Genomic research in wheat has been ongoing for two decades, facing complexity due to its large and repetitive genome.
  • Previous efforts yielded partial genome information, limiting comprehensive genetic analysis and breeding applications.

Purpose of the Study:

  • To chronicle the key milestones in wheat genomics research over the past 20 years.
  • To highlight the recent achievement of complete wheat genome sequencing.
  • To emphasize the potential of this new genomic resource for accelerating crop improvement.

Main Methods:

  • Review of published literature and research progress in wheat genomics.
Keywords:
T2Tgenome sequencinggenomicswheat

More Related Videos

Untargeted Liquid Chromatography-Mass Spectrometry-Based Metabolomics Analysis of Wheat Grain
07:10

Untargeted Liquid Chromatography-Mass Spectrometry-Based Metabolomics Analysis of Wheat Grain

Published on: March 13, 2020

10.5K
Obtaining High-Quality Transcriptome Data from Cereal Seeds by a Modified Method for Gene Expression Profiling
07:18

Obtaining High-Quality Transcriptome Data from Cereal Seeds by a Modified Method for Gene Expression Profiling

Published on: May 21, 2020

7.9K

Related Experiment Videos

Last Updated: Jan 9, 2026

Development of Targeting Induced Local Lesions IN Genomes TILLING Populations in Small Grain Crops by Ethyl Methanesulfonate Mutagenesis
08:36

Development of Targeting Induced Local Lesions IN Genomes TILLING Populations in Small Grain Crops by Ethyl Methanesulfonate Mutagenesis

Published on: July 16, 2019

12.2K
Untargeted Liquid Chromatography-Mass Spectrometry-Based Metabolomics Analysis of Wheat Grain
07:10

Untargeted Liquid Chromatography-Mass Spectrometry-Based Metabolomics Analysis of Wheat Grain

Published on: March 13, 2020

10.5K
Obtaining High-Quality Transcriptome Data from Cereal Seeds by a Modified Method for Gene Expression Profiling
07:18

Obtaining High-Quality Transcriptome Data from Cereal Seeds by a Modified Method for Gene Expression Profiling

Published on: May 21, 2020

7.9K
  • Analysis of key technological advancements enabling large-scale genome sequencing.
  • Synthesis of historical data from early genome drafts to complete sequences.

    • Main Results:

    • Publication of two articles in 2025 reporting complete wheat genome sequences marks a major milestone.
    • Significant progress has been made from early genome drafts to high-quality, complete sequences.
    • The availability of complete genome sequences provides an unprecedented resource for wheat research.

    Conclusions:

    • The completion of the wheat genome sequence represents a pivotal advancement in plant genomics.
    • This comprehensive genomic resource is expected to significantly accelerate breeding programs and enhance wheat varieties.
    • Future research will leverage these sequences to address challenges in wheat cultivation, including climate resilience and yield optimization.