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[Digital, DICOM, diagnostics-unity over chaos : Data communication in digital pathology].
Christoph Blattgerste1,2, Maximilian Legnar3, Cleo-Aron Weis3
1Computational Pathology Heidelberg, Institut für Pathologie, Uniklinikum Heidelberg, Im Neuenheimer Feld 224, 69120, Heidelberg, Deutschland. christoph.blattgerste@uni-heidelberg.de.
Digitizing pathology slides for AI diagnostics faces standardization challenges. Implementing the Digital Imaging and COmmunications in Medicine (DICOM) format with an open-source pipeline enables interoperable digital pathology workflows.
Area of Science:
- Digital pathology
- Medical imaging
- Artificial intelligence in healthcare
Background:
- Digitization of histological specimens is crucial for advanced computer-assisted analysis and AI-driven diagnostics.
- Lack of standardization and interoperability between proprietary formats and clinical systems (PACS, LIS) hinders digital pathology adoption.
- The Digital Imaging and COmmunications in Medicine (DICOM) format offers a potential solution for integrating image data, metadata, and analysis results.
Purpose of the Study:
- To address the lack of standards in digital pathology.
- To demonstrate a practical implementation of DICOM-compliant workflows for whole slide images and AI results.
- To establish a foundation for standardized, transparent, and trustworthy digital pathology.
Main Methods:
- Literature review on digital and computer-assisted pathology, focusing on DICOM adoption.
- Development and implementation of an open-source, modular Docker pipeline.
- Demonstration of DICOM-compliant workflows for storing and visualizing whole slide images and AI results.
Main Results:
- A growing body of literature supports the use of DICOM in digital pathology.
- Successful practical implementation of DICOM-compliant workflows using an open-source pipeline.
- Demonstrated capability for storing and visualizing whole slide images and AI results in a standardized format.
Conclusions:
- DICOM is emerging as a key format for enabling interoperability in digital pathology.
- The developed Docker pipeline facilitates standardized, transparent, and trustworthy digital pathology.
- This work provides a basis for wider adoption of digital pathology solutions.
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