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[Digital, DICOM, diagnostics-unity over chaos : Data communication in digital pathology]
Christoph Blattgerste1,2, Maximilian Legnar3, Cleo-Aron Weis3
1Computational Pathology Heidelberg, Institut für Pathologie, Uniklinikum Heidelberg, Im Neuenheimer Feld 224, 69120, Heidelberg, Deutschland. christoph.blattgerste@uni-heidelberg.de.
Abstract:
Digitization of histological specimens enables new computer-assisted analysis and artificial intelligence (AI)-supported diagnostics, but is hampered by a lack of standards. Interoperability between proprietary formats and clinical systems such as the Picture Archiving and Communication System (PACS) or Laboratory Information Systems (LIS) poses a particular challenge. The Digital Imaging and COmmunications in Medicine (DICOM) format, adapted from radiology, offers an open, vendor-independent solution that integrates image data, metadata, and analysis results and enables interoperable exchange. A literature review shows a growing number of publications on digital and computer-assisted pathology, with DICOM increasingly being discussed as a key format. With an open-source, modular Docker pipeline, we demonstrate the practical implementation of DICOM-compliant workflows for storing and visualizing whole slide images and AI results. This creates the basis for standardized, transparent, and trustworthy digital pathology.
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