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Published on: April 14, 2020
Optical Dissymmetry of As-Grown Twisted Paracetamol Crystals
Hengyu Zhou1, Melissa Tan1, Akash Tiwari1
1Department of Chemistry and the Molecular Design Institute, New York University, New York, New York, USA.
Abstract:
Paracetamol crystalline form III grows just above the glass transition temperature as aggressively twisted fibers that thicken in successive stages, forming complex assemblies. The growth direction is parallel to a glide plane leading to heterochiral crystals. These enantiomorphs are not Pasteur-like polyhedra with hemihedral facets that are the tell-tale signs of dissymmetric form; here every surface is dissymmetric. The chiroptical properties of the heterochiral forms are assayed as they evolve directly in the solid state using complete polarimetry.
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