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Updated: Jan 9, 2026

Synthesis of Indoxyl-glycosides for Detection of Glycosidase Activities
Published on: May 27, 2015
Visible-light-promoted O-glycosylation with indolylthio glycosides
Tianyu Zhang1, Zefei Fan1, Yongyan Fu1
1School of Chinese Materia Medica, Yunnan University of Chinese Medicine, Kunming, 650500, Yunnan, China.
Abstract:
A novel method for the preparation of thioglycoside donors from d-glucose and 2-indolone was developed. This method is straightforward to operate and enables highly efficient catalysis under mild conditions. In addition, a method for O-glycosylation of thioglycosides with various alcohols using trifluoromethyl thianthrenium triflate (TT-CF3+TfO-) as an initiator and a visible light-induced photoredox catalysis method was also developed. The method is green, mild, easy to perform and does not require a neutralization step.
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