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An Update to the Clinical Pharmacogenetics Implementation Consortium (CPIC) SLCO1B1 Allele Functionality Table
Akinyemi Oni-Orisan1, Sook Wah Yee2, Tanushree Haldar1
1Department of Clinical Pharmacy, University of California San Francisco, San Francisco, California, USA.
None:
The Clinical Pharmacogenetics Implementation Consortium (CPIC) has formally updated the SLCO1B1 allele functionality table based on new evidence. Notably, the alleles studied (SLCO1B1 *9, *31, *41) are enriched in the genomes of patients historically excluded from pharmacogenomics research. This perspective illustrates how new evidence can advance clinical pharmacogenetics implementation guidelines incorporation in real time through collaboration with CPIC. Together, we can accelerate the translation of pharmacogenetics into a tool that truly improves health outcomes for everyone.
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