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Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
Published on: January 21, 2020
The Mystery Plaque: Unraveling a Singular Perioral Granulomatous Enigma
Nishtha Mishra1, Sarthak Bansal, Asharbh Raman
1Department of Dermatology, Venereology and Leprosy, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed to be University, Pune, Maharashtra, India.
Abstract:
A 34-year-old lactating woman presented with erythematous indurated plaques around the perioral region, extending to the nose and forehead, mimicking granulomatous dermatoses. Dermoscopy showed follicular plugging and dermal inflammation. Histopathology revealed epithelioid cell granulomas with giant cells and nerve infiltration, confirming borderline tuberculoid leprosy. The patient was treated with multidrug therapy and closely monitored for reactions. This case underscores the diagnostic challenge of Hansen's disease with atypical centrofacial presentation and emphasizes the importance of histopathological confirmation for timely treatment, particularly in vulnerable groups such as lactating mothers.
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