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Grenz Ray Therapy for Porokeratosis Ptychotropica: A Case Report
Conor Larney1, Dale Jobson1,2, Belinda Welsh3
1Department of Dermatology, St Vincent's Hospital Melbourne, Melbourne, VIC, Australia.
Introduction:
Porokeratosis ptychotropica (PP) is a rare form of porokeratosis that poses significant diagnostic and therapeutic challenges. Given the rarity of PP, there is a paucity of evidence about effective treatment options. We present the first case of PP being managed with Grenz therapy (a type of superficial, low radiation radiotherapy).
Case Presentation:
Our patient was a 56-year-old female with PP in the intergluteal cleft and on her right posterior thigh. She was previously unsuccessfully treated with topical, intralesional and oral corticosteroids, topical vitamin D analogues, topical simvastatin-cholesterol cream, topical fluorouracil cream, acitretin, and CO2 laser assisted photodynamic therapy. She underwent Grenz therapy for 6 sessions, a total dose of 18 Gy to all affected areas, with excellent clinical response. After 2 months of remission, her porokeratosis showed early signs of recurrence.
Conclusion:
This is the first reported case of PP being treated with Grenz rays. With no effective treatment, Grenz therapy may present a potential effective treatment for some patients.
