Related Experiment Video
Updated: Jan 9, 2026

An In vitro Co-infection Model to Study Plasmodium falciparum-HIV-1 Interactions in Human Primary Monocyte-derived Immune Cells
Published on: August 15, 2012
Fatal Mpox Coinfection in Advanced AIDS: A Case Report
Yansi Lu1,2, Xiaoshu Yu1, Changjing Zhou1
1Department of Infectious Diseases, Baise People's Hospital, Baise, Guangxi, People's Republic of China.
None:
The mpox virus (MPXV) is a zoonotic pathogen that has been causing a worldwide pandemic outbreak since 2022, posing a significant threat to global public health security. During this outbreak, monkeypox has been more prevalent among immunocompromised individuals, particularly those infected with HIV (Human Immunodeficiency Virus). We report a case of a 21-year-old male patient with advanced AIDS in China who developed severe complications, including skin tissue infection, proctitis, and conjunctivitis, following monkeypox infection. Despite early aggressive treatment, the patient ultimately succumbed to infectious shock and multiple organ failure. This case strongly underscores that such patients experience severe skin infections and rapid disease progression, necessitating urgent early recognition and treatment.
Related Concept Videos
Retrovirus Life Cycles
Pneumonia III: Complications and Assessment
Pulmonary Tuberculosis IV
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Pulmonary Tuberculosis III
The first classification is based on the development of the disease, and it includes the following categories:
Pulmonary Tuberculosis I
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pulmonary Tuberculosis II
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...

