Is it possible to predict the response to therapy in enuretic children? The PiFe score
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View abstract on PubMed
Summary
This summary is machine-generated.Comorbidities like learning disorders and encopresis predict poor treatment response in children with nocturnal enuresis (NE). A new PiFe score helps predict outcomes and guide interventions for this common childhood condition.
Area Of Science
- Pediatrics
- Urology
- Child Psychology
Background
- Nocturnal enuresis (NE) affects children over five, with unclear causes including developmental, genetic, and physiological factors.
- Comorbidities are suspected to influence NE management and treatment success.
Purpose Of The Study
- To investigate the impact of comorbidities on nocturnal enuresis.
- To develop a predictive scoring system for treatment response in NE patients.
Main Methods
- Recruited 374 children (5-18 years) undergoing pharmacological treatment for NE.
- Collected demographic and clinical data via parent interviews.
- Utilized descriptive statistics, chi-squared tests, and logistic regression for analysis.
Main Results
- Learning disorders were associated with NE recurrence and predicted poor treatment response.
- Encopresis, polythelia, language delay, and snoring also predicted poor treatment response.
- The PiFe score was developed to integrate comorbidities, age, and severity for outcome prediction.
Conclusions
- A holistic approach is crucial for managing NE, considering associated comorbidities.
- The PiFe score offers a potential clinical tool for predicting NE treatment outcomes.
- Further research is recommended for validation and refinement of the PiFe score.
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