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Flavivirus Nonstructural Protein 1‑Driven Coagulation via Tissue Factor-Bearing Microvesicles: A Pilot Study.

Silvia Beltrami1, Matteo Ferraresi1, Giorgia Cianci1

  • 1Department of Environmental and Prevention Sciences, University of Ferrara, Ferrara 44121, Italy.

ACS Omega
|December 1, 2025
PubMed
Summary

Flavivirus nonstructural protein sNS1 influences blood clotting and inflammation differently depending on the virus type. Neurotropic flavivirus sNS1 promotes clotting, while hemorrhagic flavivirus sNS1 inhibits it, impacting disease severity.

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